ICSI is direct injection of a sperm into an egg. It bypasses the process that a sperm needs to penetrate through multiple cells layers and the egg membrane. Initially ICSI was developed for the cases with very low amount of sperm called oligozoospermia. But later, in order to prevent unexpected no fertilization by conventional insemination, ICSI became the main insemination procedure worldwide. Also, in the pre-implantation genetic testing era, ICSI is the choice insemination procedure to prevent contamination of genetic testing. More than 70% of insemination cases are performed by ICSI in the USA.


In Harvest Fertility we use the best new techniques and equipment to perform ICSI. Our lab scientists’ knowledge, skills and experiences help our patients to have the most safe and effective results with ICSI procedure*.

Who can benefit from ICSI?
⦁ Advanced maternal age
⦁ Diminished ovarian reserve
⦁ Low sperm count
⦁ No sperm in semen and obligation to use testicular sperm
⦁ Poor or zero sperm motility (movement)
⦁ Abnormally shaped sperm
⦁ Males with vasectomy or unsuccessful vasectomy reversal
⦁ Any Pre-implantation Genetic test cases
⦁ Sex selection cases

*Wun, WS, Mangal R, Bukowski E, Vanijgul C, Chauhan R, Wun IC. Negative impact of non-male factor ICSI can be alleviated by capacitated/acrosome reacted spermatozoa. Gynecology & Reproductive Health 2019; 3(5) 1-4